Medtronic- Patient Monitoring Divsion- BIS™ brain monitoring system By providing insight into the direct and patient-specific effects of anesthesia on the brain, the BIS™ brain monitoring system helps clinicians determine and administer the precise amount of drug to meet the needs of each individual patient, leading to increased patient anesthesia satisfaction. Advanced monitoring for improved outcomes Bispectral Index™ (BIS™) technology was the first clinically proven and commercially available direct measure of the effects of anesthetics and sedatives on the brain. BIS™ technology enables medical professionals to reliably gauge the precise amount of anesthetic medication required by each patient, resulting in better overall patient care.